Dr. Glen Barber’s Laboratory, situated within the Ohio State University Comprehensive Cancer Center (OSUCCC) and the Pelotonia Institute for Immuno-Oncology (PIIO), is devoted to studying cellular sensing mechanisms that trigger host defense countermeasures in response to microbial infection. This has included his discovery of a signaling pathway controlled by a new innate immune regulator referred to as STING (stimulator of interferon genes) that is activated by DNA based microbes such as viruses, bacteria, and parasites. He is interested in developing viral oncolytic agents and immunotherapeutic for the treatment of cancer and understanding the role of innate immunity & the control of cancer and Understanding mechanisms of inflammation associated cancer.
We are looking for a highly motivated individual to join the Barber Lab as a Research Senior Associate at the OSUCCC and PIIO. The Research Senior Associate will function as a technical expert in cancer immunology and immunotherapy, working closely with the principal investigator (PI) to develop project goals, execute research experiments independently, and play a major role in the dissemination of research findings. The Researcher 2 will collaborate with research staff internal and external to the lab, so strong organizational and communication skills are key. Must be able to adapt to new technologies and able to operate in a fast-paced work environment.
Essential Duties Breakdown:
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Works collaboratively with the PI to conceptualize, manage, and execute research projects; designs and conducts intricate research activities, with a focus on cancer immunology and immunotherapy procedures, including but not limited to cell culture, cytotoxicity assays, apoptosis analysis, transfection with plasmid DNA/siRNA, immunohistochemistry and immunocytochemistry, cloning, nucleic acid isolation, PCR/qPCR, subcellular fractionation/LD isolation, immunoprecipitation, Western Blot, primary cell isolation, animal model research (including small animal surgery/hepatocyte isolation) and husbandry.
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Analyzes research literature; authors and prepares manuscripts, articles, abstracts, and research reports for publication in scientific journals; presents research findings at national and international conferences and workshops; actively contributes to the writing and refinement of research grant proposals;
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Assist with lab ordering and research compliance, establishment of lab SOPs, and training of junior lab staff
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Perform other duties as required.
Education and Experience: Master's Degree in Biology, biological sciences or related field or equivalent experience required; PhD preferred. 5 years of experience in biological/health science research capacity required, 6+ years of experience preferred ; experience in a progressively responsible administrative capacity preferred; extensive experience planning & developing projects preferred; extensive knowledge and expertise in biomedical science required. Requires successful completion of a background check. Selected candidate may be requested to complete a pre-employment physical including a drug screen.
Function: Research and Scholarship
Sub Function: Research
Career Band: Individual Contributor - Specialized
Career Level: S2
Required to include in application:
Cover letter, CV, and contact information of 3 references.
Additional Information
The OSUCCC – James is the only cancer program in the United States that features a National Cancer Institute (NCI)-designated comprehensive cancer center aligned with a nationally ranked academic medical center and a freestanding cancer hospital on the campus of one of the nation’s largest public universities. The Pelotonia Institute for Immuno-Oncology (PIIO) is a comprehensive bench-to-bedside research initiative focused on harnessing the body’s immune system to fight cancer at all levels —from prevention to treatment and survivorship.
Salary range for this position: $55,100 - $72,400 annual salary
Regular 40 First Shift